Sound-induced enhancement of low-intensity vision: multisensory influences on human sensory-specific cortices and thalamic bodies relate to perceptual enhancement of visual detection sensitivity.
Sound-induced enhancement of low-intensity vision: multisensory influences on human sensory-specific cortices and thalamic bodies relate to perceptual enhancement of visual detection sensitivity.
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DOI：
10.1523/jneurosci.4524-09.2010
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发表时间：
2010-10-13
期刊：
影响因子：
--
通讯作者：
Driver J
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文献类型：
--
作者：
Noesselt T;Tyll S;Boehler CN;Budinger E;Heinze HJ;Driver J
跨通道组合信息可能会影响感觉性能。我们研究了共生声音如何调节对强度较高或较低的视觉刺激的行为视觉检测灵敏度(d‘)和神经反应。声音的共同出现增强了人类对较低强度但不是较高强度视觉目标的检测灵敏度。功能磁共振成像将此与活动水平的提高联系在一起--感觉特定的视觉和听觉皮质，加上多感觉颞叶上沟(STS)，当与声音配对时，特别是针对较低强度的视觉事件。视觉通路、听觉通路、外侧膝状体(LGB)和内侧膝状体(MGB)的丘脑结构也表现出类似的模式。逐个受试者的心理物理益处与视觉、听觉和多感官区域的相应fMRI信号相关。我们还分析了在不同的实验条件下，LGB和MGB与其他区域的不同“耦合”模式。有效连接性分析显示，在增强检测低强度视觉事件与声音配对的过程中，特定感觉的丘脑体与受影响的皮质部位的耦合增强。视觉和听觉丘脑与皮质区域(包括STS)之间的耦合强度随特定多感官环境的心理物理益处而参数变化。我们的结果表明，对低对比度视觉刺激检测灵敏度的多感觉增强通过共生声音反映了一个大脑网络，该网络不仅涉及已建立的多感觉STS和感觉特定皮质，而且还涉及视觉和听觉丘脑。
Combining information across modalities can affect sensory performance. We studied how co-occurring sounds modulate behavioral visual detection sensitivity (d’), and neural responses, for visual stimuli of higher or lower intensity. Co-occurrence of a sound enhanced human detection sensitivity for lower- but not higher-intensity visual targets. fMRI linked this to boosts in activity-levels for sensory-specific visual and auditory cortex, plus multisensory superior temporal sulcus (STS), specifically for a lower-intensity visual event when paired with a sound. Thalamic structures in visual and auditory pathways, the lateral and medial geniculate bodies respectively (LGB, MGB) showed a similar pattern. Subject-by-subject psychophysical benefits correlated with corresponding fMRI-signals in visual, auditory and multisensory regions. We also analysed differential ‘coupling’ patterns of LGB and MGB with other regions in the different experimental conditions. Effective-connectivity analyses showed enhanced coupling of sensory-specific thalamic bodies with the affected cortical sites during enhanced detection of lower-intensity visual events paired with sounds. Coupling strength between visual and auditory thalamus with cortical regions, including STS, co-varied parametrically with the psychophysical benefit for this specific multisensory context. Our results indicate that multisensory enhancement of detection sensitivity for low-contrast visual stimuli by co-occurring sounds reflects a brain network involving not only established multisensory STS and sensory-specific cortex, but also visual and auditory thalamus.