Actinopyrones A, B and C, new physiologically active substances. I. Producing organism, fermentation, isolation and biological properties.
Actinopyrones A, B and C, new physiologically active substances. I. Producing organism, fermentation, isolation and biological properties.
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Actinopyrones A、B 和 C，新的生理活性物质。
DOI：
10.7164/antibiotics.39.32
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
T. Nakashima
中科院分区：
文献类型：
--
作者：
K. Yano;K. Yokoi;J. Sato;J. Oono;T. Kouda;Y. Ogawa;T. Nakashima
发现一株能产生新的生理活性物质的链霉菌。对活性化合物进行了分离纯化，得到放线菌酮A、B和C三种物质。放线吡喃酮类化合物对麻醉犬的冠状动脉有舒张作用，对革兰氏阳性菌和皮肤癣菌的抗菌活性较弱。
A strain of Streptomyces was found to produce new physiologically active substances. The active compounds were purified and separated into three substances named actinopyrones A, B and C. Actinopyrones exhibited coronary vasodilating activities in anesthetized dogs and weakly antimicrobial activities against some Gram-positive bacteria and dermatophytes.