The dynamics of cortical interactions in visual recognition of object category: living versus nonliving
The dynamics of cortical interactions in visual recognition of object category: living versus nonliving
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DOI：
10.1093/cercor/bhac456
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发表时间：
2022-11-20
期刊：
影响因子：
3.7
通讯作者：
Ikeda，Akio
中科院分区：
文献类型：
--
作者：
Usami，Kiyohide;Matsumoto，Riki;Ikeda，Akio
非侵入性脑成像研究表明，对物体的更高程度的视觉处理发生在可根据广泛的语义类别进行分离的神经群体中，特别是有生命的物体和无生命的物体。然而，由于时间分辨率有限，这些研究无法确定广泛的语义类别是否也反映在皮质网络内神经相互作用的动态中。我们研究了 12 名在癫痫手术前植入硬膜下电极网格的患者在物体命名过程中激活的皮质区域中的神经传播的时间过程，特别关注任务的视觉识别阶段。对事件相关因果关系的分析表明，与非生命物体相比，生命物体在早期潜伏期（约 250 毫秒）的腹侧颞叶 (VTL) 内的位点之间的神经传播明显更强。其他特征的差异，包括熟悉度、视觉复杂性和习得年龄，并没有显着改变神经传播的模式。我们的研究结果表明，生物体的视觉处理依赖于 VTL 内位点之间更强的因果相互作用，这或许反映了视觉特征处理的更大程度的整合。反过来，这可能有助于解释影响 VTL 的神经系统疾病中命名生命体的脆弱性。
Noninvasive brain imaging studies have shown that higher visual processing of objects occurs in neural populations that are separable along broad semantic categories, particularly living versus nonliving objects. However, because of their limited temporal resolution, these studies have not been able to determine whether broad semantic categories are also reflected in the dynamics of neural interactions within cortical networks. We investigated the time course of neural propagation among cortical areas activated during object naming in 12 patients implanted with subdural electrode grids prior to epilepsy surgery, with a special focus on the visual recognition phase of the task. Analysis of event-related causality revealed significantly stronger neural propagation among sites within ventral temporal lobe (VTL) at early latencies, around 250 ms, for living objects compared to nonliving objects. Differences in other features, including familiarity, visual complexity, and age of acquisition, did not significantly change the patterns of neural propagation. Our findings suggest that the visual processing of living objects relies on stronger causal interactions among sites within VTL, perhaps reflecting greater integration of visual feature processing. In turn, this may help explain the fragility of naming living objects in neurological diseases affecting VTL.