Hepatitis B surface antigen in pancreatic and biliary secretions.
Hepatitis B surface antigen in pancreatic and biliary secretions.
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DOI：
10.5555/uri:pii:0016508580901298
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发表时间：
1980
期刊：
影响因子：
29.4
通讯作者：
J. Hoefs;I. Renner;M. Askhcavai;A. Redeker
中科院分区：
文献类型：
--
作者：
J. Hoefs;I. Renner;M. Askhcavai;A. Redeker
本文对26例急性（15）和慢性（11）乙型肝炎感染患者行胰管和胆总管逆行插管，获得纯胰汁（PPJ）和纯胆汁（PBJ），并对标本进行HBsAg检测。15例急性感染患者中有8例检测到乙肝表面抗原，10例慢性感染患者中有3例检测到乙肝表面抗原。10例急性B型感染患者中有7例检测到HBsAg， 5例慢性B型感染患者中仅有2例检测到HBsAg。由于正常PPJ对HBsAg检测有抑制作用，提示HBsAg阳性PPJ代表病毒大量排泄。
Pure pancreatic juice (PPJ) and pure bile (PBJ) were obtained by endoscopic retrograde cannulation of the pancreatic duct and common bile duct in 26 patients with acute (15) and chronic (11) hepatitis B infections and the specimens were tested for HBsAg. HBsAg was detected in PPJ in 8 of 15 patients with acute infections and 3 of 10 with chronic infections. HBsAg was detected in PBJ in 7 of 10 with acute infections and only 2 of 5 with chronic type B infection. Since normal PPJ was shown to be inhibitory to the detection of HBsAg, it is suggested that the HBsAg-positive PPJ represents heavy viral excretion.