DYE COUPLING AND POSSIBLE ELECTROTONIC COUPLING IN THE GUINEA-PIG NEOCORTICAL SLICE
DYE COUPLING AND POSSIBLE ELECTROTONIC COUPLING IN THE GUINEA-PIG NEOCORTICAL SLICE
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DOI：
10.1126/science.7444449
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发表时间：
1981-01-01
期刊：
影响因子：
56.9
通讯作者：
PRINCE, DA
中科院分区：
文献类型：
--
作者：
GUTNICK, MJ;PRINCE, DA
将荧光染料 Lucifer Yellow CH 离子电渗注射到豚鼠新皮质切片的单个神经元中，导致超过 1 个细胞被染色。染料耦合神经元聚集体仅在浅层皮质层中发现，并且通常组织成垂直柱状。逆向刺激在一些表层细胞中引起全有或全无的阈下去极化。这些电位不会被 Mn 消除，也不会与源自体细胞的尖峰发生碰撞，这表明它们是由浅表皮质神经元之间的电紧张相互作用产生的。
Iontophoretic injection of the fluorescent dye Lucifer Yellow CH into single neurons of guinea pig neocortical slices resulted in the staining of more than 1 cell. Dye-coupled neuronal aggregates were found only in the superficial cortical layers and were often organized in vertical columns. Antidromic stimuli evoked all-or-none, subthreshold depolarizations in some superficial cells. These potentials were not eliminated by Mn and did not collide with spikes originating in the soma, suggesting that they arose from electrotonic interaction between superficial cortical neurons.