Sleep disturbances as predictors of hospitalization for back disorders -: A 28-year follow-up of industrial employees
Sleep disturbances as predictors of hospitalization for back disorders -: A 28-year follow-up of industrial employees
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DOI：
10.1097/01.brs.0000193902.45315.e5
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发表时间：
2006-01-01
期刊：
影响因子：
3
通讯作者：
Leino-Arjas, P
中科院分区：
文献类型：
--
作者：
Kaila-Kangas, L;Kivimäki, M;Leino-Arjas, P
研究设计。一项前瞻性队列研究。探讨睡眠障碍与严重背部疾病致住院的关系。背景资料摘要。睡眠障碍与持续性疼痛综合征有关，但对其与背部疾病的关系知之甚少。1973年至2000年首次因背部疾病住院的金属工业工人队列（n = 902）进行了研究。基线时睡眠障碍的发生分为：无；1型（夜间入睡/醒来困难或做噩梦）；或者两种都有。采用Cox比例风险回归来估计评估危险因素与背部疾病首次住院之间的时间。与没有睡眠障碍的人相比，有一种睡眠障碍的人背部相关住院的风险是2.1倍（95%可信区间为1.1-3.8），两种睡眠障碍的人住院的风险是2.4倍（1.2-4.6）。风险比为2.1；1.0-4.6和2.9；当基线时排除慢性背部疾病或复发性背部症状的患者时，分别为1.2-7.1。这些发现表明睡眠障碍预示着背部疾病的住院治疗。这种关联背后的机制值得进一步研究。
Study Design. A prospective cohort study.Objective. To study the relationship of sleep disturbances with severe back disorders leading to hospitalization.Summary of Background Data. Sleep disturbances are associated with persistent pain syndromes, but little is known about their relationship with back disorders.Methods. The first hospital admission for back disorders from 1973 to 2000 was studied in a cohort of metal industry workers (n = 902). The occurrence of sleep disturbances at baseline was categorized as: none; 1 type (either difficulties in falling asleep/waking up at night or nightmares); or both types. Cox proportional hazards regression was used to estimate the time between the assessment of risk factors and first hospital admission for back disorders.Results. Those individuals who had 1 type of sleep disturbance had a 2.1-fold (95% confidence interval 1.1-3.8) risk of back-related hospitalization, and those with both types of disturbance a 2.4-fold (1.2-4.6) risk, compared with those with no sleep disturbances. The hazard ratios were 2.1; 1.0-4.6 and 2.9; 1.2-7.1, respectively, when patients with chronic back disease or recurrent back symptoms at baseline were excluded from the analyses.Conclusion. These findings suggest that sleep disturbances are predictive of hospitalization for back disorders. The mechanism underlying this association warrants further study.