A descriptive model of the receptor potential nonlinearities generated by the hair cell mechanoelectrical transducer.

A descriptive model of the receptor potential nonlinearities generated by the hair cell mechanoelectrical transducer.
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毛细胞机电换能器产生的受体电位非线性的描述性模型。

DOI:
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发表时间:
1998
影响因子:
2.4
通讯作者:
Ian J. Russell
Ian J. Russell
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
A. Lukashkin;Ian J. Russell

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本文描述了一种基于二阶玻尔兹曼函数的毛细胞受体电位模型。该模型只包括毛细胞膜的电阻元件,电池横跨它们和通过耳蜗组织的换能器电流的外部返回路径的串联电阻。该模型提供了一个定性的描述毛细胞换能器的信号处理,并表明,毛细胞换能器的非线性可以引起非线性现象,如互调失真产品和双音抑制与那些已被记录从外周听觉系统的模式类似。该模型的特定结果是证明双音抑制不依赖于受体电流的饱和度,但在接近工作点的毛细胞换能器功能的行为。该模型还表明,有非单调增长和相位变化的任何光谱分量,但没有为基本的受体电位。
This paper describes a model for generating the hair cell receptor potential based on a second-order Boltzmann function. The model includes only the resistive elements of the hair cell membranes with batteries across them and the series resistance of the external return path of the transducer current through the tissue of the cochlea. The model provides a qualitative description of signal processing by the hair cell transducer and shows that the nonlinearity of the hair cell transducer can give rise to nonlinear phenomena, such as intermodulation distortion products and two-tone suppression with patterns similar to those which have been recorded from the peripheral auditory system. Particular outcomes of the model are the demonstration that two-tone suppression depends not on the saturation of the receptor current, but on the behaviour of the hair cell transducer function close to the operating point. The model also shows that there is non-monotonic growth and phase change for any spectral component, but not for the fundamental of the receptor potential.
DOI: 10.1121/1.405619
发表时间: 1993
期刊: The Journal of the Acoustical Society of America
影响因子: --
作者:
Nuttall,AL;Dolan,DF
通讯作者: Dolan,DF
兔子 2f1-f2 畸变产物耳声发射的两个离散来源的证据:I. 对刺激参数的差异依赖性。
DOI: 10.1121/1.402440
发表时间: 1992
期刊: The Journal of the Acoustical Society of America
影响因子: --
作者:
Whitehead,ML;Lonsbury-Martin,BL;Martin,GK
通讯作者: Martin,GK