Do the adjusting-delay and increasing-delay tasks measure the same construct: delay discounting?
Do the adjusting-delay and increasing-delay tasks measure the same construct: delay discounting?
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DOI：
10.1097/fbp.0000000000000055
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发表时间：
2014-08-01
影响因子：
1.6
通讯作者：
Madden, Gregory J.
中科院分区：
文献类型：
--
作者：
Craig, Andrew R.;Maxfield, Adam D.;Madden, Gregory J.
延迟贴现描述了报酬在延迟时的主观贬值。在动物中，调整延迟(AD)和递增延迟(ID)任务经常被用来评估延迟折扣的个体差异和药物效应。然而，到目前为止，还没有研究系统地比较在这些任务中产生的贴现措施。目前的研究检查了AD和ID过程中得出的延迟折扣测量之间的相关性。在每个任务下，20只大鼠完成了30次会议(大鼠之间的顺序是平衡的)。两个任务产生的延迟折扣的量化测量呈正相关，这表明AD和ID任务测量了冲动选择的相同潜在方面(即个体或联合对奖励延迟和大小的敏感性)。然而，从任一任务中得出的衡量标准取决于任务经历的顺序。也就是说，预先接触一项任务会减少第二项任务中延迟奖励的折扣。与其他已发表的研究结果一致，在最初的贴现评估中暴露于延迟后果可能会解释这种影响。尽管观察到ID和AD无差别延迟之间的相关性，我们建议ID程序可能是一种更适合药理学研究的程序。(C)2014沃尔特斯·克鲁沃健康垂直酒吧Lippincott Williams&Wilkins。
Delay discounting describes the subjective devaluation of a reward when it is delayed. In animals, the adjusting-delay (AD) and increasing-delay (ID) tasks often are used to assess individual differences in, and drug effects on, delay discounting. No study to date, however, has compared systematically the measures of discounting produced in these tasks. The current study examined the correlation between measures of delay discounting derived from AD and ID procedures. Twenty rats completed 30 sessions under each task (order counterbalanced across rats). Quantitative measures of delay discounting produced by the two tasks were positively correlated, suggesting that the AD and ID tasks measure the same underlying facet of impulsive choice (i.e. individual or conjoint sensitivities to reward delay and magnitude). The measures derived from either task, however, depended on the sequences in which the tasks were experienced. That is, pre-exposure to one task decreased discounting of delayed rewards in the second task. Consistent with other published findings, exposure to delayed consequences during the initial discounting assessment might explain this effect. Despite the observed correlation between ID and AD indifference delays, we suggest that the ID procedure might be a more appropriate procedure for pharmacological studies. (C) 2014 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.