Regulation of adipocyte function by anthocyanins; Possibility of preventing the metabolic syndrome
Regulation of adipocyte function by anthocyanins; Possibility of preventing the metabolic syndrome
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DOI：
10.1021/jf073113b
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发表时间：
2008-02-13
影响因子：
6.1
通讯作者：
Tsuda, Takanori
中科院分区：
文献类型：
--
作者：
Tsuda, Takanori
肥胖症被定义为由各种代谢紊乱引起的过量脂肪组织的积累。脂肪细胞功能障碍与肥胖和胰岛素抵抗的发展密切相关。代谢综合征的特点是一组代谢危险因素在一个人。腹部肥胖和脂肪细胞功能障碍在该综合征的发展中起重要作用。花青素被用作一种食用色素，它们广泛分布在人类饮食中，包括浆果，这表明大量的花青素是从植物性食物中摄取的。本研究表明，花青素具有显著的抗肥胖和改善脂肪细胞功能的潜力，在体外和体内系统中，他们也有重要的意义，预防代谢综合征。
Obesity is defined as the accumulation of excess adipose tissue resulting from various metabolic disorders. Adipocyte dysfunction is strongly associated with the development of obesity and insulin resistance. Metabolic syndrome is characterized by a group of metabolic risk factors in one person. Abdominal obesity and adipocyte dysfunction play an important role in the development of this syndrome. Anthocyanins are used as a food coloring, and they are widely distributed in human diets including berries, suggesting that large amounts of anthocyanins are ingested from plant-based foods. This study shows that anthocyanins have a significant potency of antiobesity and ameliorate adipocyte function in in vitro and in vivo systems and also that they have important implications for preventing metabolic syndrome.