PSYCHOTIC SYMPTOMS AND THE LONGITUDINAL COURSE OF SENILE DEMENTIA OF THE ALZHEIMER TYPE
PSYCHOTIC SYMPTOMS AND THE LONGITUDINAL COURSE OF SENILE DEMENTIA OF THE ALZHEIMER TYPE
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DOI：
10.1016/0006-3223(89)90145-5
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发表时间：
1989-01-01
影响因子：
10.6
通讯作者：
RUBIN, EH
中科院分区：
文献类型：
--
作者：
DREVETS, WC;RUBIN, EH
妄想、误认和幻觉在阿尔茨海默型老年痴呆（SDAT）的整个病程中经常发生。在我们的研究组中，中度至重度 SDAT 受试者的精神病发生率范围为 42% 至 84%；至少有一半没有既往精神病史的 SDAT 患者会在痴呆症过程中的某个时刻表现出精神病。此外，精神病症状与认知能力加速恶化有关，但与死亡率增加无关。
Delusions, misidentifications and hallucinations occur frequently throughout the course of senile dementia of the Alzheimer type (SDAT). Rates of psychosis among subjects with moderate to severe SDAT range from 42% to 84% in our study group; at least half of persons with SDAT with no prior psychiatric history will display psychosis at some point during the course of dementia. Furthermore, psychotic symptoms are associated with accelerated cognitive deterioration, but not with increased mortality.