The prevalence and clinical significance of urethritis and cervicitis in asymptomatic people by use of multiplex polymerase chain reaction.
The prevalence and clinical significance of urethritis and cervicitis in asymptomatic people by use of multiplex polymerase chain reaction.
复制标题
DOI：
10.4111/kju.2011.52.10.703
复制
发表时间：
2011-10
期刊：
影响因子：
--
通讯作者：
Lee SJ
中科院分区：
文献类型：
--
作者：
Kim SJ;Lee DS;Lee SJ
我们的目的是通过多重聚合酶链反应（PCR）对作为性传播疾病（STD）的尿道炎或宫颈炎进行筛查，并确定沙眼衣原体、淋病奈瑟菌、生殖支原体、解脲支原体、人型支原体和阴道毛滴虫的患病率。 无症状人群。 2010年7月至2010年12月，对709名来院体检的人员进行了检测。使用 Seeplex® STD6 ACE 检测试剂盒对首次排空的尿液样本或宫颈内拭子进行多重 PCR 检测。本研究中的平均年龄为 45.4±8.1 岁。在709人中，229人（32.3%）至少一种微生物呈阳性，48人（6.8%）有两种不同的微生物，6人（0.8%）有三种不同的微生物，1人有四种不同的微生物。尿道炎或宫颈炎等无症状性传播疾病的总体患病率为 7.1% (50/709)。无症状感染者沙眼衣原体、淋病奈瑟菌、生殖支原体、解脲支原体、人型支原体、阴道毛滴虫感染患病率分别为5.6%（40/709）、0.4%（3/709）、0.3%（2/709）、22.1% 分别为 (157/709)、11.6% (82/709) 和 1.1% (8/709)。只需一个样本，我们就可以确定无症状人群中六种微生物的患病率以及尿道炎或宫颈炎的总体比例。这个比例不容忽视；因此，应建议无症状人群进行尿道炎或宫颈炎等性传播疾病的筛查检测。
Our purpose was to conduct a screening test for urethritis or cervicitis as a sexually transmitted disease (STD) by using multiplex polymerase chain reaction(PCR) and to determine the prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Ureaplasma urealyticum, Mycoplasma hominis, and Trichomonas vaginalis in asymptomatic people. From July 2010 to December 2010, 709 persons who came to the hospital for a general checkup were tested. Multiplex PCR assays were done with first voided urine samples or endocervical swabs by use of the Seeplex® STD6 ACE Detection kit. The mean age in this study was 45.4±8.1 years. Among the 709 persons, 229 (32.3%) had a positive result for at least one microorganism, 48 (6.8%) had two different species, 6 (0.8%) had three different species, and 1 person had four different species. The overall prevalence of asymptomatic STDs such as urethritis or cervicitis was 7.1% (50/709). The prevalence rates of chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Ureaplasma urealyticum, Mycoplasma hominis, and Trichomonas vaginalis infection in asymptomatic persons were 5.6% (40/709), 0.4% (3/709), 0.3% (2/709), 22.1% (157/709), 11.6% (82/709), and 1.1% (8/709), respectively. With only a single sample, we could identify the prevalence rates of six microorganisms and the overall proportion of urethritis or cervicitis in asymptomatic people. This proportion cannot be neglected; therefore, screening tests for sexually transmitted diseases such as urethritis or ervicitis should be recommended to asymptomatic people.