Ecological Measurement of Fatigue and Fatigability in Older Adults With Osteoarthritis
Ecological Measurement of Fatigue and Fatigability in Older Adults With Osteoarthritis
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DOI：
10.1093/gerona/glp137
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发表时间：
2010-02-01
影响因子：
5.1
通讯作者：
Smith, Dylan M.
中科院分区：
文献类型：
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作者：
Murphy, Susan L.;Smith, Dylan M.
疲劳与老年人失去独立性有关;然而，对最佳治疗或疲劳如何在日常生活活动中表现知之甚少。最近提出了“可重复性”来阐明疲劳-活动关系。本研究的目的是提出一种新的疲劳测量方法，并开始检验其有效性。通过生态学瞬时评估测量疲劳，每天沿着几次，同时使用腕戴式加速度计连续测量身体活动。与对照组相比，OA参与者在高活动间隔后疲劳增加的可能性约为4倍（37.0% vs 9.8%）。在OA患者中，平均疲劳和易疲劳性没有高度相关性（r = 0.13）。疲劳与报告的身体功能，疼痛和活力最密切相关，而易疲劳性与体重指数，OA严重程度和膝关节强度最密切相关，尽管OA患者的疲劳与身体功能和症状的主观报告相关，但将疲劳报告与身体活动配对可能与日常生活活动的生物力学需求相关的客观因素。因此，疲劳测量可能有助于辨别症状与日常生活功能的关系，并有助于改进OA的治疗方法。
Fatigue is associated with loss of independence in older adults; however, little is known about optimal treatment or how fatigue manifests in daily life activities. "Fatigability" was recently proposed to clarify the fatigue-activity relationship. The purpose of this study was to present a new measurement method of fatigability and begin to test its validity.Our sample included 40 adults with knee or hip osteoarthritis (OA) and 20 healthy controls. Fatigue was measured by ecological momentary assessment several times a day along with continuous measurement of physical activity using a wrist-worn accelerometer. Fatigability was measured as the fatigue increase after a period of high activity.Compared with controls, participants with OA were approximately four times more likely to have an increase in fatigue after a high activity interval (37.0% vs 9.8%). Among people with OA, average fatigue and fatigability were not highly related (r = .13). Fatigue was most strongly associated with reported physical function, pain, and vitality, whereas fatigability was most strongly associated with body mass index, OA severity, and knee strength.Although fatigue among people with OA was more associated with subjective reports of physical function and symptoms, pairing fatigue reports with physical activity tapped objective factors that may be related to the biomechanical demands of daily life activities. Thus, fatigability measurement may help discern how symptoms relate to daily life function and help to refine treatment approaches in OA.