POSITIVE CONTROL OF CYCLIC-AMP ON MESENCHYMAL FACTOR CONTROLLED DNA-SYNTHESIS IN EMBRYONIC PANCREAS

POSITIVE CONTROL OF CYCLIC-AMP ON MESENCHYMAL FACTOR CONTROLLED DNA-SYNTHESIS IN EMBRYONIC PANCREAS
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DOI:
10.1038/257702a0
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发表时间:
1975-01-01
期刊:
影响因子:
64.8
通讯作者:
RUTTER, WJ
RUTTER, WJ
中科院分区:
综合性期刊1区
文献类型:
--
作者:
FILOSA, S;PICTET, R;RUTTER, WJ

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越来越多的证据表明,环AMP和/或环GMP参与调节许多代谢过程,包括细胞增殖1 -13。本文报道了环磷酸腺苷、环磷酸鸟苷和间充质因子(MF)14- 17对器官培养的胚胎上皮细胞DNA合成的影响。
THERE is increasing evidence that cyclic AMP and/or cyclic GMP are involved in the regulation of a number of metabolic processes including cell proliferation1–13. We report here the results of an investigation testing the effects of cyclic AMP, cyclic GMP and the mesenchymal factor (MF)14–17on the stimulation of DNA synthesis in embryonic epithelia in organ culture.