Epidemiology and outcomes of osteoporotic fractures
Epidemiology and outcomes of osteoporotic fractures
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DOI：
10.1016/s0140-6736(02)08657-9
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发表时间：
2002-05-18
期刊：
影响因子：
168.9
通讯作者：
Melton, LJ
中科院分区：
文献类型：
--
作者：
Cummings, SR;Melton, LJ
随着年龄的增长，骨量会下降，骨折的风险会增加，特别是在女性进入更年期的时候。髋部骨折是骨质疏松症最严重的后果，由于世界人口老龄化，而且髋部骨折的频率正在以每年1-3%的速度增加，因此比以往更加频繁。髋部骨折的发生率在不同地区之间的差异比脊柱骨折的发生率更大。低骨密度和既往骨折是几乎所有类型骨折的危险因素，但每种类型的骨折也有自己独特的危险因素。用药物预防骨折可能与治疗骨折一样昂贵。因此，应该进行流行病学研究，并使用它来确定骨折致残的高危个体，从而使昂贵的治疗能够谨慎地分配给最需要帮助的个人。
Bone mass declines and the risk of fractures Increases as people age, especially as women pass through the menopause. Hip fractures, the most serious outcome of osteoporosis, are becoming more frequent than before because the world's population is ageing and because the frequency of hip fractures is increasing by:1-3% per year in most areas of the world. Rates of hip fracture vary more widely from region to region than does the prevalance of vertebral fractures. Low bone density and previous fractures are risk factors for almost all types of fracture, but each type of fracture also has its own unique risk factors. Prevention of fractures with drugs could potentially be as expensive as medical treatment of fractures. Therefore, epidemiological research should be done and used to identify individuals at high-risk of disabling fractures, thereby allowing careful allocation of expensive treatments to individuals most in need.