Three-dimensional time-resolved optical tomography of a conical breast phantom
Three-dimensional time-resolved optical tomography of a conical breast phantom
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DOI：
10.1364/ao.40.003278
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发表时间：
2001-07-01
期刊：
影响因子：
1.9
通讯作者：
Delpy, DT
中科院分区：
文献类型：
--
作者：
Hebden, JC;Veenstra, H;Delpy, DT
一个32通道的时间分辨成像设备的医学光学断层扫描已被用来评估一个计划，为人类女性乳房成像。全自动仪器和重建程序已在具有组织等效光学特性的圆锥体模上进行了测试。成像方案的设计旨在避免乳房受压和耦合液的需要。从实验数据中产生的图像与迭代重建算法，采用三维（3D）有限元扩散为基础的前向模型。嵌入区域的两倍的背景光学特性显示在单独的三维吸收和散射图像的幻影。三维时间分辨光学断层扫描的乳房的影响进行了讨论。(C)2001年美国光学学会。
A 32-channel time-resolved imaging device for medical optical tomography has been employed to evaluate a scheme for imaging the human female breast. The fully automated instrument and the reconstruction procedure have been tested on a conical phantom with tissue-equivalent optical properties. The imaging protocol has been designed to obviate compression of the breast and the need for coupling fluids. Images are generated from experimental data with an iterative reconstruction algorithm that employs a three-dimensional (3D) finite-element diffusion-based forward model. Embedded regions with twice the background optical properties are revealed in separate 3D absorption and scattering images of the phantom. The implications for 3D time-resolved optical tomography of the breast are discussed. (C) 2001 Optical Society of America.