Swahili translation and validation of the patient health questionnaire-9 depression scale in the Kenyan head and neck cancer patient population
Swahili translation and validation of the patient health questionnaire-9 depression scale in the Kenyan head and neck cancer patient population
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DOI：
10.2190/8w7y-0tpm-jvgv-qw6m
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发表时间：
2006-01-01
影响因子：
2
通讯作者：
Yueh, B.
中科院分区：
文献类型：
--
作者：
Omoro, S. A. O.;Fann, J. R.;Yueh, B.
背景：抑郁症是头颈部癌症患者治疗后生活质量的重要预测指标。此外，不同文化的抑郁症患病率可能会有所不同。目的：作为一项关于H&N癌症患者治疗后生活质量差异的更大跨文化研究的一部分，该项目的目标是将经过充分验证的英语语言抑郁量表翻译成斯瓦希里语，然后在肯尼亚H&N癌症患者中验证该量表。方法、设置和研究对象：在研究的第一部分，我们遵循国际生活质量协会(IQOLA)的指导方针，将患者健康问卷-9(PHQ-9)翻译成斯瓦希里语。在第二部分中，我们对肯尼亚内罗毕肯雅塔国家医院耳鼻喉科诊所的48名患者进行了前瞻性研究，对新翻译的量表进行了心理测量学验证。结果：斯瓦希里语PHQ-9具有良好的重测信度(组内相关系数为0.71)和内部一致性(Cronbach‘sα=0.80)。该量表还具有良好的结构效度，其得分与TNM分期(卡方=123，p<；0.05)、H&N癌症特异性生活质量量表的综合得分和总体得分(UW-QOL，r=-0.87，p<；0.05)显著相关。结论：斯瓦希里语版PHQ-9在肯尼亚H&N癌症患者中是一个可靠的量表，是筛查和监测该人群中抑郁与生活质量相关的有价值的工具。
Background: Depression is an important predictor of post therapy quality of life (QOL) in head and neck (H&N) cancer patients. In addition, depression rates may vary among cultures. Objective: As part of a larger cross cultural study on post therapy QOL differences in H&N cancer patients, the goal of this project was to translate a well-validated English language depression scale into Swahili, and then validate this scale in Kenyan H&N cancer patients. Methods, Settings and Subjects: In Part 1 of the study, we translated the Patient Health Questionnaire-9 (PHQ-9) into Swahili, adhering to established International Quality of Life Association (IQOLA) guidelines. In Part 2, we psychometrically validated the newly translated scale using a prospective study of 48 patients at the Kenyatta National Hospital ENT clinic in Nairobi, Kenya. Results: The Swahili PHQ-9 had good test retest reliability (Intraclass correlation coefficient, 0.71) and internal consistency (Cronbach's alpha = 0.80). It also had good construct validity, as scores correlated strongly with TNM stage (Chi square = 123, p < 0.05), and with the composite and global scores of an H&N cancer specific QOL scale (UW-QOL, r = -0.87, p < 0.05). Conclusion: The Swahili version of the PHQ-9 is a reliable scale in Kenyan H&N cancer patients, and is a valuable tool in screening for and monitoring of depression as a function of QOL in this population.