Morphology and permeability properties of blood capillaries in extraocular muscles of macaque monkeys.
Morphology and permeability properties of blood capillaries in extraocular muscles of macaque monkeys.
复制标题
猕猴眼外肌毛细血管的形态和通透性特性。
DOI：
10.1007/bf02150567
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Raviola,G
中科院分区：
文献类型：
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作者：
Mwasi,LM;Raviola,G
外源性眼肌在其纤维形态和对药物的反应方面与其他骨骼肌非常不同。此外，他们还拥有异常丰富的血液供应。由于它以前曾报道，眼外肌的毛细血管，至少部分，有孔型，骨骼肌的一个不寻常的功能，我们分析了猕猴这些血管的形态，并测试其渗透性与辣根过氧化物酶（HRP）。本文对恒河猴和猕猴上级直肌和提上睑肌的毛细血管进行了研究。fascicularishas表明这些血管在形态上与其他骨骼肌的毛细血管相似。此外，当HRP被引入静脉内时，它通过囊泡跨细胞机制被运输出血管。当HRP被注射到肌肉的间隙时，它通过相同的囊泡跨细胞转运返回到管腔。因此，大分子的双向运动可以发生在这些血管的壁上，这种运动与以前报道的其他骨骼肌没有什么不同。
Extrinsic eye muscles are very different from other skeletal muscles with regard to the morphology of their fibers and response to drugs. In addition, they are provided with an unusually rich blood supply. Since it had been previously reported that the capillaries of extraocular muscles are, at least in part, of the fenestrated type, a feature unusual for skeletal muscles, we have analyzed the morphology of these vessels in macaque monkeys and tested their permeability properties with horseradish peroxidase (HRP). Our study of the blood capillaries in the superior rectus muscle and levator palpebrae superioris inMacaca mulattaandM. fascicularishas demonstrated that these vessels are morphologically similar to the capillaries of other skeletal muscles. Furthermore, when HRP is introducedintravenam, it is transported out of the vessels by a vesicular transcellular mechanism. When HRP is injected in the interstitial spaces of the muscles, it is returned to the lumen by an identical vesicular transcellular transport. Thus, a bidirectional movement of macromolecules can take place across the walls of these vessels, and such a movement is not different from that previously reported for other skeletal muscles.