A dual-site controlled pH probe revealing the pH of sperm cytoplasm and screening for healthy spermatozoa
A dual-site controlled pH probe revealing the pH of sperm cytoplasm and screening for healthy spermatozoa
复制标题
双位点控制 pH 探针揭示精子细胞质的 pH 值并筛选健康精子
DOI：
10.1039/d1tb00108f
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发表时间：
2021-04-14
影响因子：
7
通讯作者：
Xu, Wenming
中科院分区：
文献类型：
--
作者：
Li, Xiaoliang;Wu, Sixian;Xu, Wenming
A dual-site controlled pH probe, which is composed of gold nanoparticles and modified with rhodamine and fluorescein derivatives, was applied to sensitively monitor intracellular pH changes in sperm. The pH probe revealed the intracellular pH of sperm under different conditions and demonstrated the lower pH in asthenozoospermia patients as compared to healthy individuals. Importantly, the pH probe can help screen for healthy sperm.
