Involvement of the Hippo pathway in regeneration and fibrogenesis after ischaemic acute kidney injury: YAP is the key effector.
Involvement of the Hippo pathway in regeneration and fibrogenesis after ischaemic acute kidney injury: YAP is the key effector.
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Hippo通路参与缺血性急性肾损伤后的再生和纤维形成：YAP是关键效应子
DOI：
10.1042/cs20150385
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发表时间：
2016-03
期刊：
影响因子：
--
通讯作者：
Mei CL
中科院分区：
文献类型：
--
作者：
Xu J;Li PX;Wu J;Gao YJ;Yin MX;Lin Y;Yang M;Chen DP;Sun HP;Liu ZB;Gu XC;Huang HL;Fu LL;Hu HM;He LL;Wu WQ;Fei ZL;Ji HB;Zhang L;Mei CL
Hippo通路在缺血/再灌注诱导的急性肾损伤后的再生和纤维形成中起着阶段特异性的作用。正确调控该通路可能是急性肾损伤向慢性肾脏疾病转变的关键。
The Hippo pathway plays a stage-specific role in regeneration and fibrogenesis after ischaemia/reperfusion-induced acute kidney injury. The proper modulation of this pathway might be the key point of transition from acute kidney injury to chronic kidney disease.