Isolation and characterization of a photorepair-deficient mutant in Drosophila melanogaster.
Isolation and characterization of a photorepair-deficient mutant in Drosophila melanogaster.
复制标题
果蝇光修复缺陷突变体的分离和表征。
DOI：
10.1093/genetics/116.2.233
复制
发表时间：
1987
期刊：
影响因子：
3.3
通讯作者：
Harris,PV
中科院分区：
文献类型：
--
作者：
Boyd,JB;Harris,PV
在果蝇第二条染色体上的56.8厘摩位置上发现了一个破坏光修复的突变。phr等位基因纯合的菌株完全缺乏光修复，部分缺失切除修复。这两个缺陷都定位在染色体区域。由于homozygousphrstock表现出减少的光复活，相应的野生型等位基因在紫外线抗性中起着重要作用。
A mutation abolishing photorepair has been localized to map position 56.8 centimorgans on the second chromosome ofDrosophila melanogaster. Strains homozygous for thephrallele are totally devoid of photorepair and partially deficient in excision repair. Both defects map to the chromosomal region betweenprandc. Since a homozygousphrstock exhibits reduced photoreactivation, the corresponding wild-type allele plays a significant role in UV resistance.