Consecutive case series with long-term follow-up of full macular translocation for myopic choroidal neovascularisation.

Consecutive case series with long-term follow-up of full macular translocation for myopic choroidal neovascularisation.
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连续病例系列,对近视脉络膜新生血管完全黄斑移位进行长期随访。

DOI:
10.1136/bjophthalmol-2013-304189
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发表时间:
2014
期刊:
Br J Ophthalmol.
影响因子:
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通讯作者:
Nishida K.
Nishida K.
中科院分区:
--
文献类型:
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作者:
Sakimoto S;Sakaguchi H;Ohji M;Gomi F;Ikuno Y;Fujikado T;Kamei M;Nishida K.

文献摘要

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目的探讨全黄斑移位术(FMT)治疗近视性脉络膜新生血管(mCNV)的长期疗效。方法我们对60只接受FMT的mCNV患者进行连续病例系列分析。我们评估最佳矫正视力(BCVA)、眼底照片和荧光素血管造影图像,并评估解剖和视力结果。结果平均随访76.3个月。所有患眼均成功复位黄斑。黄斑移位的平均距离为2842 μm。基线BCVA为最小分辨角(logMAR)单位的0.78对数;术后1年、3年和5年的logMAR BCVA值显著改善(p< 0.001),1年时为0.54,然后保持稳定。19只眼(31.7%)的新生中心凹与近视性脉络膜视网膜萎缩扩大有关。5眼(8.3%)在移位的新中心凹处发生中心凹下或中心凹旁CNV。结论FMT治疗mCNV可使VA改善持续5年以上。然而,术后并发症和近视所致脉络膜视网膜萎缩的进展似乎仍然限制了FMT治疗mCNV后的视力改善。
Aim To examine the long-term outcomes of full macular translocation (FMT) for myopic choroidal neovascularisation (mCNV). Methods We evaluated a consecutive case series of 60 eyes with mCNV that underwent FMT. We assessed the best-corrected visual acuity (BCVA), fundus photographs and fluorescein angiography images, and evaluated the anatomic and visual outcomes. Results The mean follow-up period was 76.3 months. The macula was relocated successfully in all eyes. The mean distance of macular translocation was 2842 μm. The baseline BCVA was 0.78 logarithm of the minimum angle of resolution (logMAR) unit; the logMAR BCVA values at 1, 3 and 5 years postoperatively significantly (p< 0.001) improved to 0.54 at 1 year and then remained stable. The new fovea was associated with enlargement of the myopic chorioretinal atrophy in 19 (31.7%) eyes. Subfoveal or juxtafoveal CNV at the translocated new fovea developed in five (8.3%) eyes. Conclusions FMT for mCNV maintained the improvement in VA for more than 5 years. However, postoperative complications and progression of chorioretinal atrophy due to myopia still seem to limit the visual improvement after FMT for mCNV.