Introversion associated with large differences between screening blood pressure and home blood pressure measurement: the Ohasama study
Introversion associated with large differences between screening blood pressure and home blood pressure measurement: the Ohasama study
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DOI：
10.1097/01.hjh.0000249695.81241.35
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发表时间：
2006-11-01
影响因子：
4.9
通讯作者：
Imai, Yutaka
中科院分区：
文献类型：
--
作者：
Hozawa, Atsushi;Ohkubo, Takayoshi;Imai, Yutaka
目的探讨个性因素对筛查临床血压和家庭血压的影响。方法1997~1999年，对699名受试者进行筛查和家庭血压测量，并完成简式艾森克个性问卷日文版。筛查血压升高定义为筛查血压=140/90 mm Hg，家庭血压升高定义为家庭血压=135/85 mm Hg。结果筛查得分较低(即内向)的受试者筛查血压与家庭收缩压差异较大。即使在调整了其他可能的因素(较年轻、女性、宽筛查脉压、从不吸烟、没有抗高血压药物)后，内向与差异之间的关联在统计学上也是显著的。调整后的SBP差值在最低和最高外向四分位数之间分别为7.3和4.4 mm Hg(趋势P=0.02)。其他个性评分(精神质或神经质)与筛查和家庭血压差异无关。在由上述影响筛查和家庭血压差异的因素组成的基本模型中加入了外向评分，略微改善了对家庭高血压的预测。与基础模型相比，高筛查血压受试者受试者工作特征曲线下面积增加0.037，筛查血压正常者受试者受试者工作特征曲线下面积增加0.006。结论内向型高血压患者在临床环境中可能存在潜在的“白大褂”高血压。
Objective To explore the effect of personality on screening blood pressures measured in clinical settings and home blood pressure measurements.Methods From 1997 to 1999, 699 participants underwent screening and home blood pressure measurements and completed the Japanese version of the short-form Eysenck personality questionnaire. An increased screening blood pressure was defined as screening blood pressure >= 140/90 mmHg and an increased home blood pressure was defined as home blood pressure >= 135/85 mmHg.Results Participants with lower extroversion scores (i.e., introversion) showed a greater difference between screening and home systolic blood pressure. The association between introversion and differences was statistically significant, even after adjustment for other possible factors (younger age, female, wide screening pulse pressure, never smoked, and no antihypertensive medication). The adjusted means of SBP differences were 7.3 and 4.4 mmHg among the lowest and highest extroversion quartiles, respectively (P for trend = 0.02). Other personality scores (psychoticism or neuroticism) were not associated with screening and home blood pressure differences. The incorporation of an extroversion score in the basic model consisting of the above factors that affected the difference between screening and home blood pressure slightly improved the prediction of a high home blood pressure. The area under the receiver operating characteristic curve increased by 0.037 among participants with high screening blood pressure and 0.006 for those with normal screening blood pressure compared with the basic model.Conclusion Physicians may need to be aware of 'introverted' patients who have high blood pressure in clinic settings, because they have the potential for 'white-coat' hypertension.