Translating the Diabetes Prevention Program into the community - The DEPLOY pilot study
Translating the Diabetes Prevention Program into the community - The DEPLOY pilot study
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DOI：
10.1016/j.amepre.2008.06.035
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发表时间：
2008-10-01
影响因子：
5.5
通讯作者：
Marrero, David G.
中科院分区：
文献类型：
--
作者：
Ackermann, Ronald T.;Finch, Emily A.;Marrero, David G.
背景资料：糖尿病预防计划（DPP）发现，强化的生活方式干预可以减少糖尿病前期成年人一半以上的糖尿病发展，但关于在社区环境中提供这种干预的可行性的信息很少。本研究评估了与基督教青年会合作开展的基于小组的DPP生活方式干预的实施情况。这项试点随机分组试验旨在比较YMCA提供的基于组的DPP生活方式干预与在两个半城市YMCA设施之一参加糖尿病风险筛查活动且BMI >= 24 kg/m（2）的成年人中单独进行的简短咨询（对照），>= 2个糖尿病风险因素，随机毛细血管血糖为110-199 mg/dL。多变量回归被用来比较组间差异的变化，体重，血压，糖化血红蛋白，总胆固醇，HDL-胆固醇后6和12 months.Results：在92名参与者中，控制更经常是女性（61%比50%）和非白人种族（29%比7%）。6个月后，干预组体重下降6.0%（95%CI =4.7，7.3），对照组体重下降2.0%（95%CI =0.6，3.3）（p
Background: The Diabetes Prevention Program (DPP) found that an intensive lifestyle intervention can reduce the development of diabetes by more than half in adults with prediabetes, but there is little information about the feasibility of offering such an intervention in community settings. This study evaluated the delivery of a group-based DPP lifestyle intervention in partnership with the YMCA.Methods: This pilot cluster-randomized trial was designed to compare group-based DPP lifestyle intervention delivery by the YMCA to brief counseling alone (control) in adults who attended a diabetes risk-screening event at one of two semi-urban YMCA facilities and who had a BMI >= 24 kg/m(2), >= 2 diabetes risk factors, and a random capillary blood glucose of 110-199 mg/dL. Multivariate regression was used to compare between-group differences in changes in body weight, blood pressures, HbAlc, total cholesterol, and HDL-cholesterol after 6 and 12 months.Results: Among 92 participants, controls were more often women (61% vs 50%) and of nonwhite race (29% vs 7%). After 6 months, body weight decreased by 6.0% (95% CI=4.7, 7.3) in intervention participants and 2.0% (95% CI=0.6, 3.3) in controls (p