Optimal Viewing Angle Determination for Multiple Vessel Segments in Coronary Angiographic Image
Optimal Viewing Angle Determination for Multiple Vessel Segments in Coronary Angiographic Image
复制标题
冠状动脉造影图像中多个血管段的最佳视角确定
DOI：
10.1109/tns.2014.2319336
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发表时间：
2014-06-01
影响因子：
1.8
通讯作者：
Wang, Yongtian
中科院分区：
文献类型：
--
作者：
Wang, Xuehu;Yang, Jian;Wang, Yongtian
血管造影图像是全身从三维空间到二维成像平面的透视投影，其中使用X射线。因此，拓扑脉管系统信息已经丢失。在2D血管造影中，在管状结构中通常观察到透视缩短和重叠。因此，应确定最佳视角，以从有限数量的血管造影图像中观察具有最小化透视缩短和重叠的感兴趣血管段（IVS）或感兴趣血管分叉（IVB）。在这项研究中，提出了一种新的综合优化方法来计算最佳视角。在所提出的方法中，考虑了血管的不规则形状和分支间距离。此外，三个优化条件，包括投影缩短率，投影狭窄率，投影重叠率，设计和集成，以确定在一个单一的血管段的最佳视角。三个条件，包括投影缩短，投影狭窄，投影相邻间距率，也被设计为优化分叉的视角。为了评估所提出的方法的性能，我们模拟了基于X射线传播原理的血管造影图像，通过集成3D冠状动脉树模型和相应的CT体积数据。实验结果表明，该方法是非常有效和鲁棒的，因此，该方法可以用来确定最佳视角的IVS或IVB不规则狭窄。该方法也可以帮助医生在临床实践中更清楚地观察分支结构或狭窄。
Angiographic image is the perspective projection of the whole body from a 3D space to a 2D imaging plane, in which X-ray is used. As such, topological vasculature information has been lost. In 2D angiograms, foreshortening and overlapping are commonly observed in tubular-like structures. Hence, an optimum viewing angle should be determined to observe an interesting vessel segment (IVS) or an interesting vessel bifurcation (IVB) with minimized foreshortening and overlapping from a limited number of angiographic images. In this study, a novel integrated optimization method is proposed to calculate the optimum viewing angle. In the proposed method, the irregular shape and inter-branch distance of vasculatures are considered. Furthermore, three optimized conditions, including projection foreshortening rate, projection stenosis rate, and projection overlapping rate, are designed and integrated to determine the optimum viewing angle in a single vessel segment. The three conditions, including projection foreshortening, projection stenosis, and projection adjacent spacing rates, are also designed to optimize the viewing angle of bifurcations. To evaluate the performance of the proposed method, we simulated an angiographic image based on X-ray propagating principle by integrating 3D coronary artery tree models and the respective CT volume data. Experimental results demonstrate that the proposed method is very effective and robust; hence, this method can be used to determine the optimum viewing angle of IVS or IVB with irregular stenosis. The proposed method can also help physicians observe the branching structure or stenosis clearly in clinical practice.