Plaque components at coronary sites with focal spasm in patients with variant angina: Virtual histology-intravascular ultrasound analysis
Plaque components at coronary sites with focal spasm in patients with variant angina: Virtual histology-intravascular ultrasound analysis
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DOI：
10.1016/j.ijcard.2009.04.042
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发表时间：
2010-10-29
影响因子：
3.5
通讯作者：
Kang, Jung Chaee
中科院分区：
文献类型：
--
作者：
Hong, Young Joon;Jeong, Myung Ho;Kang, Jung Chaee
背景资料：我们比较了30例变异型心绞痛（VA）患者与32例不稳定型心绞痛（UA）患者冠状动脉病变部位麦角新碱激发试验后局灶性痉挛的斑块成分，采用虚拟组织学血管内超声（VH-IVUS）将组织分为四个主要成分：纤维化、纤维脂肪、致密钙（DC）和坏死核心（NC）。薄帽纤维动脉粥样硬化（TCFA）定义为至少3个连续帧中NC >= 10%斑块面积，无覆盖纤维组织，斑块负荷>= 40%。
Background: We compared the plaque components at coronary sites with focal spasm after ergonovine provocation test in 30 variant angina (VA) patients with those at culprit coronary sites in 32 unstable angina (UA) patients using virtual histology-intravascular ultrasound (VH-IVUS).Methods: VH-IVUS classified and color-coded tissue into four major components: fibrotic; fibro-fatty; dense calcium (DC); and necrotic core (NC). Thin-cap fibroatheroma (TCFA) was defined as a NC >= 10% of plaque area in at least 3 consecutive frames without overlying fibrous tissue in the presence of >= 40% plaque burden.Results: The lesion site plaque burden was significantly smaller (44.5+/-10.8% vs. 70.5+/-13.1%, p