Value of Ultrasound in Preoperative Local Staging in Early Breast Cancer
Value of Ultrasound in Preoperative Local Staging in Early Breast Cancer
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DOI：
10.1055/s-0029-1245243
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发表时间：
2011-08-01
影响因子：
3.4
通讯作者：
Sauer, G.
中科院分区：
文献类型：
--
作者：
Varga, D.;Woeckel, A.;Sauer, G.
目的：本研究的目的是确定与组织学测量相比，乳腺超声测量乳腺病变的精度。还分析了许多其他因变量。材料和方法：使用乳腺超声检查 460 名患者的 445 个恶性病变，测量病变并与组织学测量的大小进行比较。根据组织学、肿瘤分期、年龄、分级和治疗进一步分析数据。结果：指标比较显示超声检查与病理测量的乳腺病灶大小之间具有良好的相关性，特别是在肿瘤分期 T1 和 T2 以及导管浸润性癌中。较高的肿瘤分期导致测量不精确，小叶浸润性癌的组织学类型也会导致测量不精确。年龄和分级不影响测量精度。结论：乳腺超声可以精确测量乳腺病变，特别是在较低的肿瘤阶段。肿瘤分期越高，测量就越不精确。多变量分析显示肿瘤分期和组织学类型之间对测量质量没有交叉影响。
Purpose: The purpose of this study was to determine the precision of breast ultrasound for the measurement of breast lesions compared to the histological measurement. A number of other dependent variables were also analyzed. Material and Methods: 460 patients with 445 malignant lesions were examined using breast ultrasound and the lesions were measured and compared to the histologically measured size. The data was further analyzed according to histology, tumor stage, age, grading and therapy.Results: Metric comparison showed good correlation between sonography and the pathologically measured size of breast lesions, especially in tumor stage T1 and T2 and within ductal invasive carcinomas. Higher tumor stages lead to imprecise measurements and the histological type of lobular invasive carcinoma also results in imprecise measurements. Age and grading do not influence measurement precision.Conclusion: Breast ultrasound allows precise measurement of breast lesions especially at lower tumor stages. The higher the tumor stage, the more imprecise the measurement becomes. Multivariate analysis shows no cross impact between tumor stage and histological type with respect to the quality of measurement.