Current status of atopic dermatitis in Japan.
Current status of atopic dermatitis in Japan.
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DOI：
10.5415/apallergy.2011.1.2.64
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发表时间：
2011-07
影响因子：
1.7
通讯作者：
Takeuchi S
中科院分区：
文献类型：
--
作者：
Furue M;Chiba T;Takeuchi S
特应性皮炎（AD）是一种常见的、慢性或慢性复发性、严重湿疹性皮肤病。AD是日本皮肤科诊所中第二常见的皮肤病。在日本大陆，儿童AD的患病率为12-13%;然而，在冲绳石垣岛的儿童中，患病率仅为一半（约6%）。局部类固醇和他克莫司是治疗的主要药物。然而，长期使用局部类固醇的副作用和情感恐惧在全世界的患者中引起了“局部类固醇恐惧症”。治疗不足可加重面部/眼周病变，并因反复抓挠/摩擦/拍打而导致特应性白内障和视网膜脱离的发生。通过教育、患者及其监护人的理解和合作，克服局部类固醇恐惧症是成功治疗AD的关键。
Atopic dermatitis (AD) is a common, chronic or chronically relapsing, severely pruritic, eczematous skin disease. AD is the second most frequently observed skin disease in dermatology clinics in Japan. Prevalence of childhood AD is 12-13% in mainland Japan; however, it is only half that (about 6%) in children from Ishigaki Island, Okinawa. Topical steroids and tacrolimus are the mainstay of treatment. However, the adverse effects and emotional fear of long-term use of topical steroids have induced a "topical steroid phobia" in patients throughout the world. Undertreatment can exacerbate facial/periocular lesions and lead to the development of atopic cataract and retinal detachment due to repeated scratching/rubbing/patting. Overcoming topical steroid phobia is a key issue for the successful treatment of AD through education, understanding and cooperation of patients and their guardians.