Genomic dark matter sheds light on EVI1-driven leukemia.
Genomic dark matter sheds light on EVI1-driven leukemia.
复制标题
基因组暗物质揭示了 EVI1 驱动的白血病。
DOI:
10.1016/j.ccr.2014.03.031
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发表时间:
2014
期刊:
影响因子:
50.3
通讯作者:
Armstrong,ScottA
中科院分区:
文献类型:
--
作者:
Koche,RichardP;Armstrong,ScottA
The orchestration of transcriptional programs depends on proper gene-enhancer pairing. While much remains to be learned about this process in normal development, two recent studies inCell(Gröschel and colleagues) and this issue ofCancer Cell(Yamazaki and colleagues) highlight how the genomic rearrangement of an enhancer plays a causal role in the onset of a leukemogenic program.
影响因子:
64.5
作者:
Groeschel, Stefan;Sanders, Mathijs A.;Delwel, Ruud
通讯作者:
Delwel, Ruud