Analysis of human vaginal secretions using rabbit anti-human vaginal secretions: detection of non-serum proteins.
Analysis of human vaginal secretions using rabbit anti-human vaginal secretions: detection of non-serum proteins.
复制标题
使用兔抗人阴道分泌物分析人阴道分泌物：非血清蛋白的检测。
DOI：
--
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Y. Itoh
中科院分区：
文献类型：
--
作者：
Y. Itoh
用兔抗阴道分泌物(HVS)血清分析了人阴道分泌物(HVS)中可检测到的抗原。该抗血清被一批人血清吸收后，经免疫电泳法分析，在人血清白蛋白和抗血清之间产生了三条沉淀线。这些谱线位于丙种球蛋白区(a线)、β-伽马区(b线)和贝塔区(c线)。在来自50名妇女的59份人类免疫缺陷病毒标本中，它们的出现频率分别为46(78%)、56(95%)和29(49%)。在这些HVS标本中，57例(97%)对其中一种或多种抗原呈阳性。这三种抗原a、b和c可被认为是确定人类免疫缺陷病毒存在与否的有用标记物。文中还讨论了人类免疫缺陷病毒蛋白的来源以及来自上生殖道的非血清蛋白的影响。
The antigens detectable in human vaginal secretions (HVS) have been analyzed by using a rabbit anti-HVS serum. After absorption by a pool of human sera, this antiserum on immunoelectrophoretic analysis produced three precipitation lines between the HVS and the antiserum. These lines were found at gamma (a line), beta-gamma (b line) and beta (c line) globulin regions. Their respective incidences of appearance among 59 HVS specimens obtained from 50 women were 46 (78%), 56 (95%) and 29 (49%). Of these HVS specimens, 57 (97%) were positive for one or more of these antigens. These three antigens, a, b, and c can be considered useful markers to determine the presence of the HVS. The origin of the HVS proteins and the influence of the non-serum proteins from the upper genital tracts are also discussed.