Relapsing polychondritis with different types of ocular inflammations
Relapsing polychondritis with different types of ocular inflammations
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DOI：
10.2147/imcrj.s89507
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发表时间：
2015-01-01
影响因子：
0.9
通讯作者：
Yamamoto, Shuichi
中科院分区：
文献类型：
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作者：
Furuya, Nana;Oshitari, Toshiyuki;Yamamoto, Shuichi
我们提出了两个案件复发性多囊炎（RP）与不同类型的眼部炎症。第一个病例是一名35岁的男性，他有双侧结膜充血和眼痛，被转介到千叶大学医院，诊断为难治性巩膜外层炎。患者接受地塞米松滴眼液治疗。他出现耳鸣、双耳耳聋和左耳廓炎。左耳廓活检显示软骨周围淋巴细胞浸润。他被诊断为RP，并接受30 mg/天口服泼尼松龙治疗。在逐渐减少泼尼松龙后，双眼的巩膜炎有所改善。第二个病例是一名71岁的男子，他双耳失聪，患有双侧巩膜炎。第一次来我院就诊时，他的左眼睑和右耳廓红肿，并报告有些疼痛。他接受静脉注射抗生素治疗，左眼眶蜂窝织炎迅速好转。然而，他出现了右侧巩膜炎和左侧膝关节炎。磁共振成像显示双侧后巩膜炎和右耳软骨膜炎。耳部活检显示淋巴细胞浸润到耳周组织中。他被诊断为RP，给予40 mg/天口服泼尼松龙，他的症状改善。虽然RP是罕见的，但它是一种危及生命的疾病。因此，眼科医生应考虑RP患者的眼睛和耳朵炎症。
We were presented with two cases of relapsing polychondritis (RP) associated with different types of ocular inflammation. The first case was a 35- year- old man who had bilateral hyperemic conjunctiva and ocular pain, and was referred to Chiba University Hospital with a diagnosis of episcleritis refractory. He was treated with dexamethasone eye drops. He developed tinnitus, deafness in both ears, and left auriculitis. A left auricular biopsy showed an infiltration of lymphocytes surrounding the cartilage. He was diagnosed with RP and treated with 30 mg/day oral prednisolone. After tapering the prednisolone, the scleritis in both eyes improved. The second case was a 71-year-old man who was deaf in both ears and had bilateral scleritis. At the first visit to our hospital, his left eyelid and right auricula were reddish and swollen, and he reported some pain. He was treated with intravenous antibiotics, and the left orbital cellulitis quickly improved. However, he developed right scleritis and left gonitis. Magnetic resonance imaging showed bilateral posterior scleritis and right auricular perichondritis. Auricular biopsy showed an infiltration of lymphocytes into the periauricular tissue. He was diagnosed with RP, and 40 mg/ day oral prednisolone was given and his symptoms improved. Although RP is rare, it is a life-threatening disease. Thus, ophthalmologists should consider RP in patients with both ocular and auricular inflammation.