Giant cell arteritis and polymyalgia rheumatica in a region of Finland: an epidemiologic, clinical and pathologic study, 1984-1988.

Giant cell arteritis and polymyalgia rheumatica in a region of Finland: an epidemiologic, clinical and pathologic study, 1984-1988.
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芬兰某地区的巨细胞动脉炎和风湿性多肌痛:一项流行病学、临床和病理学研究,1984-1988 年。

DOI:
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发表时间:
1992
影响因子:
3.9
通讯作者:
J. von Knorring
J. von Knorring
中科院分区:
医学2区
文献类型:
--
作者:
P. Franzén;S. Sutinen;J. von Knorring

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调查了芬兰西尼兰州巨细胞性动脉炎(GCA)(以颞动脉炎和风湿性多肌痛为表现)的发生。在1984至1988年间,在约44,500人中诊断出54名患者。14名患者(26%)在最初评估时有活检证实的动脉炎,2名患者在随访中活检阳性。回顾确定的44个月期间GCA的年发病率在整个人口中为22.5/10(5),在50岁或以上的居民中为69.8/10(5)。16个月前瞻性研究的相应数字分别为30.4/10(5)和94.4/10(5)。前瞻性研究的发病率高于同类研究中报道的发病率。风湿性多发性肌痛是GCA最常见的表现,占87%。
The occurrence of giant cell arteritis (GCA) (considering temporal arteritis and polymyalgia rheumatica as its manifestations) was investigated in Western Nyland, Finland. Between 1984 and 1988 54 patients were diagnosed in a population of about 44,500. Fourteen patients (26%) had biopsy proven arteritis at the initial evaluation, and 2 patients became biopsy positive during followup. The retrospectively determined annual incidence of GCA in a 44 month period was 22.5/10(5) in the whole population, and 69.8/10(5) in residents aged 50 years or older. The corresponding figures of a prospective 16 month study were 30.4/10(5) and 94.4/10(5). The incidence rates of the prospective study are higher than those reported in comparable studies. Polymyalgia rheumatica, occurring alone or combined with cranial symptoms, was the most frequent manifestation of GCA, being present in 87% of patients.