536. Transformations of 2-methyl-Δ2-oxazoline in aqueous solution
536. Transformations of 2-methyl-Δ2-oxazoline in aqueous solution
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536. 2-甲基-Δ2-恶唑啉在水溶液中的转化
DOI：
10.1039/jr9600002686
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发表时间：
1960
期刊：
影响因子：
--
通讯作者：
J. Schofield
中科院分区：
文献类型：
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作者：
G. Porter;H. Rydon;J. Schofield
2-甲基- a2 -恶唑啉部分中和溶液的pH值随时间变化，先快速上升后缓慢下降；这些变化是由于首先转化为o -乙酰乙醇胺，然后转化为n -乙酰乙醇胺。根据所涉及的反应速率得出结论，2-甲基- a2 -恶唑啉不是水溶液中0-转化为n -乙酰乙醇胺的中间体。为了另一个目的，我们需要知道2-甲基- a2 -恶唑啉（Ib）的碱性强度，我们试图通过测量部分中和的碱水溶液的pH值来确定它。人们注意到，这些溶液的pH值随着时间的推移而迅速变化，尽管通过将观察到的pH值外推到零，可以令人满意地评估pK，但随着时间的推移，酸性溶液变为碱性，然后又变为酸性的现象似乎值得研究。
The pH of partially neutralised solutions of 2-methyl-A2-oxazoline changes with time, an initial rapid rise being followed by a slower fall; these changes are shown to be due to conversion into, first, O-acetylethanolamine, and then into N-acetylethanolamine. On the basis of the rates of the reactions involved it is concluded that 2-methyl-A2-oxazoline is not an intermediate in the conversion of 0-into N-acetylethanolamine in aqueous solution.REQUIRING, for another purpose> to know the basic strength of 2-methyl-A2-oxazoline (Ib), we attempted to determine this by the usual procedure of measuring the pH of partially neutralised aqueous solutions of the base. It was noticed that the pH of such solutions changed rapidly with time and, although pK, was satisfactorily evaluated by extrapolation of the observed pH values to zero time, the phenomenon of an acid solution that became alkaline and then acid again with the mere passage of time seemed to warrant investigation.