QCT/FEA predictions of femoral stiffness are strongly affected by boundary condition modeling.
QCT/FEA predictions of femoral stiffness are strongly affected by boundary condition modeling.
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DOI：
10.1080/10255842.2015.1006209
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发表时间：
2016
影响因子：
1.6
通讯作者：
Dragomir-Daescu D
中科院分区：
文献类型：
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作者：
Rossman T;Kushvaha V;Dragomir-Daescu D
基于定量计算机断层扫描的股骨近端有限元模型在用于评估骨关节炎患者骨折风险之前，必须通过尸体实验进行验证。在验证过程中，必须仔细评估边界条件建模是否与实验条件相匹配。本研究评估了近端股骨刚度的预测结果，通过六种不同的边界条件的方法对样本的30具尸体股骨，并与实验数据的预测进行了比较。在六种边界条件下，平均刚度变化280%。与实验数据相比，预测范围从高估65%的平均刚度低估41%。此外，我们发现，边界条件，分布的负载接触表面类似于预期的接触力学预测与实验刚度的最佳协议。我们得出结论，边界条件建模在近端股骨刚度预测中引入了较大的变化。
Quantitative computed tomography-based finite element models of proximal femora must be validated with cadaveric experiments before using them to assess fracture risk in osteoporotic patients. During validation it is essential to carefully assess whether the boundary condition modeling matches the experimental conditions. This study evaluated proximal femur stiffness results predicted by six different boundary condition methods on a sample of 30 cadaveric femora and compared the predictions with experimental data. The average stiffness varied by 280% among the six boundary conditions. Compared with experimental data the predictions ranged from overestimating the average stiffness by 65% to underestimating it by 41%. In addition we found that the boundary condition that distributed the load to the contact surfaces similar to the expected contact mechanics predictions had the best agreement with experimental stiffness. We concluded that boundary conditions modeling introduced large variations in proximal femora stiffness predictions.