Effect of Smoking Cessation on Mean Platelet Volume
Effect of Smoking Cessation on Mean Platelet Volume
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DOI：
10.1177/1076029612436675
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发表时间：
2013-06-01
影响因子：
2.9
通讯作者：
Dogan, Abdullah
中科院分区：
文献类型：
--
作者：
Varol, Ercan;Icli, Atilla;Dogan, Abdullah
本研究的目的是评估经常吸烟者的平均血小板体积（MPV）值以及戒烟对MPV的影响。研究组包括116名经常吸烟者（57名女性和59名男性;平均年龄46.3 ± 12.7岁），对照组包括90名健康志愿者（49名女性和41名男性;平均年龄47.7 ± 8.3岁）。在经常吸烟者和对照参与者中评估血小板指数。在这101名参与者戒烟后3个月测量血小板指数。吸烟者的MPV值显著高于对照组（分别为8.8 +/- 0.9和8.0 +/- 0.8 fL; P <0.001）。与基线值相比，MPV值在3个月时显著降低（分别为8.9 +/- 1.0 vs 7.9 +/- 0.7 fL; P <0.001）。我们发现，血清MPV值显着高于经常吸烟者比对照组。戒烟3个月后，血清MPV值显著降低。
The aim of this study was to assess the values of mean platelet volume (MPV) in regular smokers and the effect of smoking cessation on MPV. The study group consisted of 116 regular smokers (57 females and 59 males; mean age 46.3 +/- 12.7 years) and the control group was composed of 90 healthy volunteers (49 females and 41 males; mean age 47.7 +/- 8.3 years). Platelet indices were assessed in regular smokers and control participants. Platelet indices were measured at 3 months after smoking cessation in these 101 participants. The MPV values were significantly higher in smokers than those of controls (8.8 +/- 0.9 vs 8.0 +/- 0.8 fL, respectively; P < .001). The MPV values decreased significantly at 3 months when compared with the baseline values (8.9 +/- 1.0 vs 7.9 +/- 0.7 fL, respectively; P < .001). We have found that serum MPV values were significantly higher in regular smokers than in controls. Serum MPV values decreased significantly at 3 months after smoking cessation.