Quantifying the disease transmission function: effects of density on Batrachochytrium dendrobatidis transmission in the mountain yellow-legged frog Rana muscosa.
Quantifying the disease transmission function: effects of density on Batrachochytrium dendrobatidis transmission in the mountain yellow-legged frog Rana muscosa.
复制标题
量化疾病传播函数：密度对山黄腿蛙 Rana muscosa 中 Batrachochytrium dendrobatidis 传播的影响。
DOI：
10.1111/j.1365-2656.2007.01256.x
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Briggs,CherylJ
中科院分区：
文献类型：
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作者：
Rachowicz,LaraJ;Briggs,CherylJ
1.鞭毛菌病是一种新出现的两栖动物传染病，由真菌病原菌树突巴氏杆菌引起，近年来在全球范围内与种群数量下降和可能的灭绝有关。2.通过实验室和野外实验，量化了该病原菌在山地黄腿蛙体内的传播率，并用最大似然法确定了实验数据最能支持的传播函数形式。3.在传染病中，被感染的粉虱蝌蚪的寄主比例随着它们所接触的先前感染粉虱蝌蚪的数量而增加。4.实验室实验表明，传播率随着感染者密度的增加而趋于平稳的传播函数得到了一定的支持。然而，没有足够的功率来区分传输函数的频率相关形式和其他几种渐近形式。5.还研究了拥挤和温度对传播率的影响，但这两个因素对传播率都没有显著影响。
1. Chytridiomycosis is an emerging infectious disease of amphibians, caused by the fungal pathogen Batrachochytrium dendrobatidis, which has been implicated recently in population declines and possible extinctions throughout the world. 2. The transmission rate of this pathogen was quantified in the mountain yellow-legged frog Rana muscosa through laboratory and field experiments, and a maximum likelihood approach was used to determine the form of the transmission function that was best supported by the experimental data. 3. The proportion of R. muscosa tadpole hosts that became infected increased with the number of previously infected R. muscosa tadpoles to which they were exposed, as would be expected in an infectious disease. 4. The laboratory experiment revealed some support for a transmission function in which the transmission rate levels off as the density of infected individuals increases. However, there was not enough power to distinguish between a frequency-dependent form and several other asymptotic forms of the transmission function. 5. The impacts of crowding and temperature on transmission were also investigated; however, neither of these factors significantly affected the transmission rate.