Risk Factors for Adverse Pregnancy Outcomes among Zhuang Ethnic Pregnant Women: A Cohort Study in Guangxi, China
Risk Factors for Adverse Pregnancy Outcomes among Zhuang Ethnic Pregnant Women: A Cohort Study in Guangxi, China
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壮族孕妇不良妊娠结局的危险因素：中国广西的一项队列研究
DOI：
10.1007/s11596-021-2339-9
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发表时间：
2021-04-01
影响因子：
2.4
通讯作者：
Li，Han
中科院分区：
文献类型：
--
作者：
Feng，Bao-ying;Peng，Yang;Li，Han
壮族孕妇不良妊娠结局的危险因素尚不清楚。分析壮族人群早产、低出生体重儿和巨大儿的发生率及其相关危险因素。我们对9965名广西壮族孕妇进行了一项前瞻性队列研究。通过问卷调查和查阅病历获得母亲和新生儿的信息。采用多因素Logistic回归分析相关因素与不良妊娠结局的关系。结果表明，壮族人群PB、LBW和巨大儿的发生率分别为5.55%、5.64%和2.19%。母亲年龄≥36岁（OR=2.22，95%CI：1.51-3.27）与PB发生率较高相关。孕前体重指数（BMI）<18.5 kg/m2（OR=1.91，95%CI：1.45-2.51），且胎儿为女性（OR=1.74，95%CI：1.36-2.23）者，更易发生低出生体重儿。母亲年龄在31 - 35岁（OR=1.76，95%CI：1.03-2.99）和孕前超重或肥胖（OR=1.79，95%CI：1.15-2.80）与巨大儿的风险较高相关。母亲孕前BMI <18.5 kg/m2（OR=0.30，95%CI：0.15-0.60）和胎儿为女性（OR=0.41，95%CI：0.28-0.59）是巨大儿的保护因素。本研究可为壮族地区妇幼保健管理提供参考。
Risk factors for adverse pregnancy outcomes among Zhuang ethnic pregnant women are unclear. This study analyzed the incidence and risk factors related to preterm birth (PB), low birth weight (LBW) and macrosomia in Zhuang population. We conducted a prospective cohort study of 9965 Zhuang pregnancy women in Guangxi, China. Information on mothers and newborns was obtained by using questionnaires and referring to medical records. Multivariate logistic regression analyses were used to evaluate the association between related factors and adverse pregnancy outcomes. Our results showed that the incidence of PB, LBW and macrosomia in Zhuang people was 5.55%, 5.64% and 2.19%, respectively. Maternal age ≥36 years (OR=2.22, 95% CI: 1.51–3.27) was related to a higher incidence of PB. Those with pre-pregnancy body mass index (BMI) <18.5 kg/m2(OR=1.91, 95% CI: 1.45–2.51), and had a female fetus (OR=1.74, 95% CI: 1.36–2.23) were more likely to have LBW infants. Maternal age between 31 and 35 years (OR=1.76, 95% CI: 1.03–2.99) and pre-pregnancy overweight or obesity (OR=1.79, 95% CI: 1.15–2.80) were associated with a higher risk of macrosomia. The protective factors of macrosomia were maternal pre-pregnancy BMI <18.5 kg/m2(OR=0.30, 95% CI: 0.15–0.60) and female fetus (OR=0.41, 95% CI: 0.28–0.59). Our study provided a reference for maternal and childcare administration among Zhuang population.