GALAXY(Glycoanalysis by the three axes of MS and chromatography):: A web application that assists structural analyses of N-glycans
GALAXY(Glycoanalysis by the three axes of MS and chromatography):: A web application that assists structural analyses of N-glycans
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DOI：
10.4052/tigg.15.235
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发表时间：
2003-07-01
影响因子：
0.3
通讯作者：
Kato, K
中科院分区：
文献类型：
--
作者：
Takahashi, N;Kato, K
自从提出2-D/3-D HPLC图谱技术用于N-聚糖的结构分析以来，已经阐明了大约500种不同的结构。基于积累的数据，我们开发了一个网络应用程序，GALAXY（通过MS和色谱三轴糖分析），更有效地利用2-D/3-D地图。该应用程序将有助于搜索满足2-D/3-D HPLC和/或质谱数据的候选结构，并使我们能够预测推定的PA-聚糖的坐标，并以图形方式跟踪糖苷酶处理的效果。
Since the 2-D/3-D HPLC mapping technique was proposed for structural analyses of N-glycans, approximately 500 different structures have been elucidated. Based on the accumulated data, we developed a web application, GALAXY (Glycoanalysis by the three axes of MS and chromatography), to utilize the 2-D/3-D maps more effectively. This application will facilitate search of candidate structures satisfying 2-D/3-D HPLC and/or mass spectrometric data and enable us to predict coordinates of putative PA-glycans and to trace the effects of glycosidase treatments in a graphical manner.