GATE V6: a major enhancement of the GATE simulation platform enabling modelling of CT and radiotherapy
GATE V6: a major enhancement of the GATE simulation platform enabling modelling of CT and radiotherapy
复制标题
DOI：
10.1088/0031-9155/56/4/001
复制
发表时间：
2011-02-21
影响因子：
3.5
通讯作者：
Buvat, I.
中科院分区：
文献类型：
--
作者：
Jan, S.;Benoit, D.;Buvat, I.
GATE（Geant 4 Application for Emission Tomography）是一个蒙特卡罗模拟平台，由OpenGATE合作开发，自2001年以来，于2004年首次公开发布。该平台专门用于平面断层成像、单光子发射计算机断层扫描（SPECT）和正电子发射断层扫描（PET）采集的建模，广泛用于辅助PET和SPECT研究。该平台的最新扩展由OpenGATE合作发布，名为GATE V6，现在还可以进行X射线计算机断层扫描和放射治疗实验的建模。本文概述了自最初的GATE论文（Jan et al 2004 Phys. Med. Biol. 49 4543-61）发表以来，GATE中实施的主要添加和改进。这包括GATE中可用于模拟光学和强子过程的新模型，建模示踪剂，器官或探测器运动的新颖性，加速GATE模拟的新选项，说明GATE V6在放射治疗应用和CT模拟中的使用的示例，以及关于GATE V6在放射治疗应用中的验证的初步结果。在完成广泛的验证研究后，GATE有望成为涉及放射治疗和成像的模拟的有价值的工具。
GATE (Geant4 Application for Emission Tomography) is a Monte Carlo simulation platform developed by the OpenGATE collaboration since 2001 and first publicly released in 2004. Dedicated to the modelling of planar scintigraphy, single photon emission computed tomography (SPECT) and positron emission tomography (PET) acquisitions, this platform is widely used to assist PET and SPECT research. A recent extension of this platform, released by the OpenGATE collaboration as GATE V6, now also enables modelling of x-ray computed tomography and radiation therapy experiments. This paper presents an overview of the main additions and improvements implemented in GATE since the publication of the initial GATE paper (Jan et al 2004 Phys. Med. Biol. 49 4543-61). This includes new models available in GATE to simulate optical and hadronic processes, novelties in modelling tracer, organ or detector motion, new options for speeding up GATE simulations, examples illustrating the use of GATE V6 in radiotherapy applications and CT simulations, and preliminary results regarding the validation of GATE V6 for radiation therapy applications. Upon completion of extensive validation studies, GATE is expected to become a valuable tool for simulations involving both radiotherapy and imaging.