Great Britain
Great Britain
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DOI：
10.1080/00358534008451078
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发表时间：
1896-04
期刊：
影响因子：
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通讯作者：
E. Poe;Kevin J. Hayes;Edgar Allan Poe’s;Christopher Gair
中科院分区：
文献类型：
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作者：
E. Poe;Kevin J. Hayes;Edgar Allan Poe’s;Christopher Gair
研究目的：首先，在英国确定空间上接近的儿童白血病和癌症的成对和三胞胎。其次，比较配对频率与随机期望值，识别过剩，并测量任何集群的直径。第三，推断可能的原因。设计和设置分层泊松分析两套全面的儿童白血病和癌症的数据在英国：寻求家庭地址对特定的人口普查查点区（ED）或邮政编码（PC）。在不同家庭数的全国艾德分层中，将共享单个或相邻ED的白血病登记对/三联体的数量与泊松期望进行比较。在具有不同数量邮政投递点（DP）的国家PC分层中，将共享单个PC的白血病/癌症死亡（和出生）的成对/三胞胎与泊松期望进行比较。在相同的PC死亡对中单独识别相同和相邻的房屋对。区域病例密度是在指数病例样本周围估计的，使用它们自己的PC网格坐标，以及以美分记录的坐标。
Study objectives Firstly, to identify spatially close pairs and triplets of childhood leukaemias and cancers in Britain. Secondly, to compare pair frequencies with random expectations, identify excesses, and measure the diameters ofany clusters. Thirdly, to infer possible causes. Design and setting Stratified Poisson analyses of two comprehensive sets of childhood leukaemia and cancer data in Great Britain: seeking home address pairs within particular census enumeration districts (EDs) or postcodes (PCs). Numbers of pairs/triplets ofleukaemia registrations sharing single or adjacent EDs were compared with Poisson expectations in national ED strata with different numbers of households (HHs). Pairs/triplets of leukaemia/cancer deaths (and births) sharing a single PC were compared with Poisson expectations in national PC strata with different numbers ofpostal delivery points (DPs). Same and adjacent house pairs were identified individually among the same PC death pairs. Areal case densities were estimated around a sample of index cases, using their own PC grid coordinates, and those recorded in the cent-