Prediction of protein structure from amino acid sequence
Prediction of protein structure from amino acid sequence
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从氨基酸序列预测蛋白质结构
作者：
M. Sternberg;J. Thornton
从原理上讲，从蛋白质的氨基酸序列可以从理论上预测蛋白质的三维结构。最近，通过使用简单的模型来表示蛋白质构象和原子间相互作用，以及从分析已知蛋白质结构中获得的知识，朝着这一目标取得了实质性进展。
In principle, it is possible to predict theoretically the three-dimensional structure of a protein from its amino acid sequence. Recently substantial progress towards this goal has been made by the use of simple models to represent protein conformation and interatomic interactions, together with the knowledge gained from analyses of known protein structures.