Hyperparathyroidism after radioactive iodine therapy
Hyperparathyroidism after radioactive iodine therapy
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DOI：
10.1016/j.amjsurg.2007.04.005
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发表时间：
2007-09-01
影响因子：
3
通讯作者：
Clark, Orlo H.
中科院分区：
文献类型：
--
作者：
Colaco, Shanthi M.;Si, Ming;Clark, Orlo H.
背景：放射性碘（RAI）治疗被认为会引起原发性甲状旁腺功能亢进（HPT）。我们描述了一系列的患者与HPT和RAI exposure.Methods的历史：患者的人口统计学和临床信息进行了评估，包括潜伏期的发展HPT后RAI exposure.Results的：我们治疗I I患者与HPT和RAI exposure. 9例（82%）良性甲状腺疾病接受了RAI治疗。收集了英文文献中36例RAI暴露后HPT的病例进行进一步分析。在这个集体的经验，RAI治疗后的HPT的发展的平均潜伏期时间为13.5 +/- 9.1年，并被发现与RAI exposure.Conclusions年龄呈负相关：接受RAI治疗的患者有发展HPT的风险，这种风险似乎在老年患者增加。对于接受过RAI治疗的患者，建议进行血清钙监测。(c)2007 Excerpta Medica Inc. All rights reserved.
Background: Radioactive iodine (RAI) treatment has been suggested to cause primary hyperparathyroidism (HPT). We describe a series of patients with HPT and a history of RAI exposure.Methods: Patient demographic and clinical information was evaluated, including the latency time to the development of HPT after RAI exposure.Results: We treated I I patients with HPT and a history of RAI exposure. RAI treatment was administered for benign thyroid disease in 9 (82%) cases. Thirty-six cases of HPT after RAI exposure in the English literature were compiled for further analysis. In this collective experience, the average latency time to the development of HPT after RAI treatment was 13.5 +/- 9.1 years and was found to be inversely correlated with age at RAI exposure.Conclusions: Patients who undergo RAI treatment are at risk of developing HPT, and this risk appears to increase in elderly patients. Serum calcium surveillance is recommended for patients who have undergone RAI treatment. (c) 2007 Excerpta Medica Inc. All rights reserved.