The impact of verbal memory encoding and consolidation deficits during recovery from moderate-to-severe traumatic brain injury.
The impact of verbal memory encoding and consolidation deficits during recovery from moderate-to-severe traumatic brain injury.
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中度至重度创伤性脑损伤恢复过程中言语记忆编码和巩固缺陷的影响。
DOI：
10.1097/htr.0b013e318218dcf9
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Schmitter-Edgecombe,Maureen
中科院分区：
文献类型：
--
作者：
Wright,MatthewJ;Schmitter-Edgecombe,Maureen
目的：编码和巩固缺陷似乎是创伤性脑损伤（TBI）后言语记忆障碍的原因。目前尚不清楚这些能力是否在TBI恢复期间变化。我们试图确定TBI后言语编码和巩固缺陷的模式和影响。方法：23名中度至重度TBI参与者和25名年龄和教育程度匹配的对照参与者的言语记忆能力在两个时间点进行评估，大约间隔1年;评估发生在TBI幸存者的急性和慢性访视时。主要结果测量：Rey听觉言语学习测试和编码，巩固和检索缺陷的项目特异性缺陷方法指数。结果：与对照组相比，TBI参与者在两个时间点都表现出编码和巩固缺陷的言语记忆受损。TBI组的短期延迟回忆和巩固分数在急性和慢性评估之间有所改善。编码（主要）和巩固（次要）赤字出现的预测急性和慢性回忆TBI组。此外，急性访问编码赤字预测慢性访问延迟召回TBI幸存者，但急性巩固赤字没有.Conclusions：这些研究结果表明，记忆康复工作集中在改善口头材料的编码可能是有用的，在急性和慢性阶段的恢复TBI后。
Objective:Encoding and consolidation deficits appear to account for verbal memory impairment following traumatic brain injury (TBI). It is unknown whether these abilities vary during TBI recovery. We sought to determine the pattern and impact of verbal encoding and consolidation deficits following TBI.Methods:Twenty-three participants with moderate-to-severe TBI and 25 age-and education-matched control participants' verbal memory abilities were assessed at 2 time points approximately 1 year apart; assessments occurred at acute and chronic visits for TBI survivors.Main Outcome Measures:Rey Auditory Verbal Learning Test and Item Specific Deficit Approach indices of encoding, consolidation, and retrieval deficits.Results:In contrast to the controls, participants with TBI showed impaired verbal memory characterized by encoding and consolidation deficits at both time points. The TBI group's short-delayed recall and consolidation scores improved between the acute and chronic assessments. Encoding (primary) and consolidation (secondary) deficits emerged as predictors of acute and chronic recall in the TBI group. Also, acute visit encoding deficits predicted chronic visit delayed recall in TBI survivors, but acute consolidation deficits did not.Conclusions:These findings suggest that memory rehabilitation efforts focused on improving encoding of verbal material may be useful during both the acute and chronic phases of recovery following TBI.