Antibiotic use and misuse during pregnancy and delivery: benefits and risks.
Antibiotic use and misuse during pregnancy and delivery: benefits and risks.
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DOI：
10.3390/ijerph110807993
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发表时间：
2014-08-07
影响因子：
--
通讯作者：
Martinez de Tejada B
中科院分区：
文献类型：
--
作者：
Martinez de Tejada B
虽然怀孕被认为是一种生理状态，但发达国家的大多数孕妇都接受多种药物治疗，以预防孕产妇或新生儿并发症，其中抗生素是最常用的处方。在怀孕期间，抗生素通常在早产、产热、预防新生儿B群链球菌热和剖宫产的情况下使用。在此期间之外，它们通常在社区环境中用于治疗呼吸道、泌尿系统和耳鼻喉感染症状。虽然目前的一些适应症有深刻的理由来证明其使用的合理性，但与过度使用和误用相关的潜在风险可能超过其益处。值得注意的是，最近的2014年世界卫生大会对抗生素过度使用和误用造成的抗生素耐药性表示严重关切，并敦促立即采取行动，在全球范围内抗击抗生素耐药性。产科领域的大多数研究都集中在抗生素对短期孕产妇和新生儿并发症的益处上，但对长期后果的兴趣很少（如果有的话）。
Although pregnancy is considered as a physiological state, most pregnant women in developed countries receive multiple medications to prevent maternal or neonatal complications, with antibiotics among the most frequently prescribed. During pregnancy, antibiotics are often prescribed in the context of preterm labor, intrapartum fever, prevention of neonatal Group B Streptococcus fever, and cesarean section. Outside this period, they are commonly prescribed in the community setting for respiratory, urinary, and ear, nose and throat infection symptoms. Whereas some of the current indications have insightful reasons to justify their use, potential risks related to overuse and misuse may surpass the benefits. Of note, the recent 2014 World Health Assembly expressed serious concern regarding antibiotic resistance due to antibiotic overuse and misuse and urged immediate action to combat antibiotic resistance on a global scale. Most studies in the obstetrics field have focused on the benefits of antibiotics for short-term maternal and neonatal complications, but with very little (if any) interest in long-term consequences.
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