Cerium oxide nanoparticles scavenge nitric oxide radical (•NO)

Cerium oxide nanoparticles scavenge nitric oxide radical (•NO)
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DOI:
10.1039/c2cc30485f
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发表时间:
2012-01-01
影响因子:
4.9
通讯作者:
Self, William T.
Self, William T.
中科院分区:
化学2区
文献类型:
--
作者:
Dowding, Janet M.;Dosani, Talib;Self, William T.

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在这项研究中,我们获得了氧化铈纳米颗粒(CeO2 NPs)能够清除一氧化氮自由基的证据。令人惊讶的是,这种活性存在于3+状态下具有较低Ce水平的CeO2 NPs中(具有低3+/4+比的CeO2 NPs,因此氧空位数量减少),而与超氧化物清除性能形成对比的是,超氧化物清除性能与3+状态下Ce水平的增加相关(CeO2 NPs具有高3+/4+比,因此氧空位数量增加)。
In this study we have obtained evidence that cerium oxide nanoparticles (CeO2 NPs) are able to scavenge nitric oxide radical. Surprisingly, this activity is present in CeO2 NPs with a lower level of cerium in the 3+ state (CeO2 NPs with low 3+/4+ ratio and therefore a reduced number of oxygen vacancies), in contrast to the superoxide scavenging properties which are correlated with an increased level of cerium in the 3+ state (CeO2 NPs with high 3+/4+ ratio and therefore an increased number of oxygen vacancies).