A subset of cells in the nerve net of Hydra oligactis defined by a monoclonal antibody: its arrangement and development.
A subset of cells in the nerve net of Hydra oligactis defined by a monoclonal antibody: its arrangement and development.
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由单克隆抗体定义的寡水螅神经网络中的细胞子集：其排列和发育。
DOI：
10.1016/0012-1606(85)90344-6
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发表时间：
1985
影响因子：
2.7
通讯作者：
Bode,HR
中科院分区：
文献类型：
--
作者：
Dunne,JF;Javois,LC;Huang,LW;Bode,HR
一个单克隆抗体，被称为JD 1，产生绑定到一个子集的神经细胞在hypostome和触角的水螅oligactis。使用整体安装技术的神经细胞的子集和它们的过程的空间模式可以清楚地使用间接免疫荧光可视化。该亚群主要对应于表皮感觉细胞。使用相同的技术检查了头再生和萌芽过程中图案的发展。神经细胞的出现与触角和下体的形成相吻合。当头部再生不发生时，JD1+细胞不出现，这表明JD1+细胞的分化是头部形成中依赖于先行图案化过程的不可或缺的事件。
A monoclonal antibody, termed JD1, was generated that bound to a subset of the nerve cells in the hypostome and tentacles ofHydra oligactis. Using a whole-mount technique the spatial pattern of the subset of nerve cells and their processes could be clearly visualized using indirect immunofluorescence. The subset largely corresponds to the epidermal sensory cells. Using the same technique the development of the pattern during head regeneration and budding was examined. The appearance of the nerve cells coincides with the formation of both the tentacles and hypostome. When head regeneration does not occur, JD1+ cells do not appear suggesting the differentiation of JD1+ cells is an integral event in head formation dependent on antecedent patterning processes.