Risk factors for inguinal hernia in middle-aged and elderly men: Results from the Rotterdam Study
Risk factors for inguinal hernia in middle-aged and elderly men: Results from the Rotterdam Study
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DOI：
10.1016/j.surg.2014.09.029
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发表时间：
2015-03-01
期刊：
影响因子：
3.8
通讯作者：
Jeekel, Johannes
中科院分区：
文献类型：
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作者：
de Goede, Barry;Timmermans, Lucas;Jeekel, Johannes
背景关于腹股沟疝的危险因素和发病率的前瞻性数据很少，尤其是在老年人群中。本研究的目的是确定腹股沟疝的发病率和危险因素。我们分析了来自鹿特丹研究的数据，这是一项前瞻性队列研究，观察了鹿特丹的一个区Ommoord的年龄≥ 45岁的普通人群，从基线（1990年）开始超过20年。腹股沟疝的诊断是从出院记录和全科医生的记录中获得的。进行多因素回归分析以确定腹股沟疝发生的危险因素。在5,780例基线时无疝的男性中，共50,802人-年，发生了416例腹股沟疝（7.2%）。20年累积发病率为14%。腹股沟疝的危险比（HR）男性相对于女性为12.4（95%CI，9.5 - 16.3; P <0.001）。多变量分析显示，腹股沟疝的风险随着年龄的增长而增加（HR每增加1岁，1.03; 95%CI，1.02 - 1.04; P <0.001）。体重指数（BMI）为25 - 30 kg/m2的受试者的HR为0.72（95% CI，0.58 - 0.89; P =.003），而BMI为30的受试者的相关HR为0.63（95% CI，0.42 - 0.94; P =.025）。腹股沟疝常见于中老年男性人群，发病率随年龄增长而增加。超重或肥胖患者患腹股沟疝的风险较低。
Background. Prospective data on risk factors and the incidence of inguinal hernia are sparse, especially in an elderly population. The aim of this study was to determine the incidence of and risk factors for inguinal hernia.Methods. We analyzed data from the Rotterdam Study, a prospective cohort study that observed the general population aged >= 45 years of Ommoord, a district in Rotterdam, from baseline (1990) over a period of >20 years. Diagnoses of inguinal hernia were obtained from hospital discharge records and records from general practitioners. Multivariate regression analysis was performed to determine risk factors for inguinal hernia development.Results. Among 5,780 men, with a total of 50,802 person-years, who did not have a hernia at baseline, 416 cases of inguinal hernia (7.2%) occurred. The 20-year cumulative incidence was 14%. Age-adjusted hazard ratio (HR) for inguinal hernia for men relative to women was 12.4 (95% CI, 9.5-16.3; P < .001). On multivariate analysis, the risk of inguinal hernia increased with advancing age (HR per 1-year increase in age, 1.03; 95% CI, 1.02-1.04; P < .001). Participants with a body mass index (BMI) of 25-30 kg/m(2) had an HR of 0.72 (95% CI, 0.58-0.89; P = .003) compared with a BMI of 30 had an associated HR of 0.63 (95% CI, 0.42-0.94; P = .025).Conclusion. Inguinal hernia is common in the middle-aged and elderly male population and its incidence increases with advancing age. Overweight or obese patients have a lesser risk of developing an inguinal hernia.