FeCl3-Mediated Radical Tandem Reactions of 3-Benzyl-2-oxindoles with Styrene Derivatives for the Stereoselective Synthesis of Spirocyclohexene Oxindoles

FeCl3-Mediated Radical Tandem Reactions of 3-Benzyl-2-oxindoles with Styrene Derivatives for the Stereoselective Synthesis of Spirocyclohexene Oxindoles
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FeCl3 介导的 3-苄基-2-羟吲哚与苯乙烯衍生物的自由基串联反应用于螺环己烯羟吲哚的立体选择性合成

DOI:
10.1021/acs.orglett.6b00234
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发表时间:
2016
期刊:
影响因子:
5.2
通讯作者:
Li Chao-Jun
Li Chao-Jun
中科院分区:
化学1区
文献类型:
--
作者:
Wu Hong-Ru;Cheng Liang;Kong De-Long;Huang Hong-Yan;Gu Chun-Ling;Liu Li;Wang Dong;Li Chao-Jun

文献摘要

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A novel FeCl3-mediated reaction of 3-benzyl-2-oxindoles with styrene derivatives was developed. The reaction provided spirocyclohexene oxindoles in good yields and excellent diastereoselectivities via a tandem radical addition/cyclization process.