FLOTAC: A promising technique for detecting helminth eggs in human faeces
FLOTAC: A promising technique for detecting helminth eggs in human faeces
复制标题
DOI：
10.1016/j.trstmh.2009.05.012
复制
发表时间：
2009-12-01
影响因子：
2.2
通讯作者：
Utzinger, Juerg
中科院分区：
文献类型：
--
作者：
Knopp, Stefanie;Glinz, Dominik;Utzinger, Juerg
在人类蠕虫病的“预防性化疗”时代，有一种忽视诊断问题的趋势。然而，准确的诊断对于适当的病人管理和社区控制方案的监测再怎么强调也不为过。隐含的是一个诊断的困境：更有效的干预措施是在减少蠕虫卵排泄，不太敏感的直接寄生虫学测试成为。在这里，迄今为止取得的经验与FLOTAC技术诊断常见的土壤传播的蠕虫感染进行了总结。在检测低强度感染时，单个FLOTAC比多个Kato-Katz厚涂片具有更高的灵敏度。需要在不同的流行病学环境中进一步验证FLOTAC技术，包括肠道血吸虫病和食源性吸虫病的诊断。(C)2009年皇家热带医学和卫生学会。由爱思唯尔有限公司出版。保留所有权利。
There is a tendency to neglect diagnostic issues in the era of 'preventive chemotherapy' in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management and monitoring of community-based control programmes. Implicit is a diagnostic dilemma: the more effective interventions are in reducing helminth egg excretion, the less sensitive direct parasitological tests become. Here, experiences gained thus far with the FLOTAC technique for diagnosing common soil-transmitted helminth infections are summarized. A single FLOTAC has higher sensitivity than multiple Kato-Katz thick smears in detecting low-intensity infections. Further validation of the FLOTAC technique in different epidemiological settings is warranted, including diagnosis of intestinal schistosomiasis and food-borne trematodiases. (C) 2009 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.