The Minorities Risk Factors and Stroke Study (MRFASS). Design, methods and baseline characteristics.
The Minorities Risk Factors and Stroke Study (MRFASS). Design, methods and baseline characteristics.
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少数民族风险因素和中风研究 (MRFASS)。
DOI：
10.1159/000109691
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发表时间：
1997
影响因子：
5.7
通讯作者：
Weinberger,J
中科院分区：
文献类型：
--
作者：
Tuhrim,S;Godbold,JH;Goldman,ME;Horowitz,DR;Weinberger,J
非洲裔美国人和拉丁裔美国人与白色非拉丁裔美国人相比，中风的风险增加。这项研究旨在确定已知的中风风险因素是否可以解释这种风险增加。在这项病例对照研究中，对照组（社区志愿者）与急性卒中病例按种族进行组匹配，非洲裔美国人和拉丁美洲人的比例约为2：1，白人为1：1。收集了每例受试者的大量历史、临床和实验室数据。对于每一个种族群体，病例都比志愿者对照组年龄大一些，受教育程度低一些。各种族组患者从卒中发作到入院的时间、卒中严重程度、住院时间、出院处置和死亡率相似。除了少数例外，每个种族组中卒中亚型的分布与以前报告的相似。本病例对照研究的受试者招募按照计划的方式和时间范围完成。对该样本的危险因素信息进行分析，应能为研究的少数群体中与卒中主要可改变危险因素相关的相对风险提供有价值的信息。
African-Americans and probably Latinos are at increased risk of stroke compared with white, non-Latino Americans. This study seeks to determine if the known risk factors for stroke can account for this increased risk. In this case-control study controls (neighborhood volunteers) were group-matched to acute stroke cases by ethnicity in a ratio of approximately 2:1 for African-Americans and Latinos and 1:1 for whites. Extensive historical, clinical and laboratory data were collected on each subject. For each ethnic group cases were somewhat older and less well-educated than the volunteer controls. Patients in each ethnic group were similar with regard to time from stroke onset to hospital admission, stroke severity, length of stay, discharge disposition and mortality rate. With minor exceptions the distributions of stroke subtypes within each ethnic group appeared similar to those previously reported. Subject recruitment for this case-control study was completed in the manner and time frame planned. Analysis of risk factor information from this sample should provide valuable information regarding the relative risk associated with the major modifiable risk factors for stroke in the minority groups studied.