Game Theory Paradigm: A New Tool for Investigating Social Dysfunction in Major Depressive Disorders.
Game Theory Paradigm: A New Tool for Investigating Social Dysfunction in Major Depressive Disorders.
复制标题
博弈论范式：研究重度抑郁症社会功能障碍的新工具
DOI：
10.3389/fpsyt.2015.00128
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发表时间：
2015
影响因子：
4.7
通讯作者：
Zhou Y
中科院分区：
文献类型：
--
作者：
Wang Y;Yang LQ;Li S;Zhou Y
Social dysfunction is a prominent source of distress and disability in patients with major depressive disorder (MDD) but is commonly omitted from current clinical studies, although some researchers propose an evolutionary strategy to understand these negative outcomes. Limited knowledge about the neural basis of social dysfunction in MDD results from traditional paradigms, which lack insights into social interactions. Game theoretical modeling offers a new tool for investigating social-interaction impairments in neuropsychiatric disorders. This review first introduces three widely used games from game theory and the major behavioral and neuroimaging findings obtained using these games in healthy populations. We also address the factors that modulate behaviors in games and their neural bases. We then summarize the current findings obtained by using these games in depressed patients and discuss the clinical implications of these abnormal game behaviors. Finally, we briefly discuss future prospects that may further elucidate the clinical use of a game theory paradigm in MDD.
